Incidence, therapeutic response, and age and sex relationships. However, patients with “alarm signs”, such as dysphagia (difficulty in swallowing), odynophagia (painful swallowing) throat pain, weight loss and hoarseness should undergo more extensive evaluation.įor more information on Mr Modayil, his clinical interests or to arrange an appointment, please click here. Globus symptom causes a lot of anxiety among patients who are smokers or heavy drinkers. Is there a chance that this could be cancer? The most important thing to remember is that this condition is just an abnormal sensation of a lump in the throat rather than an actual growth or lump.